The Scourge Wolf is a mutated creature commonly found in areas of high radiation, such as nuclear weapon impact sites and nuclear waste collections. Scourge wolves often have patches of missing skin, revealing the muscles, and sometimes organs, underneath. They can have a very broad range of mutations, but most will form long spikes along their backs, behind their legs and at the ends of their tails.

Due to lack of a steady food source, scourge wolves will attack and eat just about anything they can kill, including other scourge wolves. However, some scourge wolves will band together in packs of two, or rarely, three, to take down larger prey.